Abstract

The turtle Pseudemys scripta elegans is able to hydroxylate and acetylate Sulphamethoxazole in a way that is comparable to man, i.e. the rate and yield of hydroxylation equals that of the acetylation. The hydroxy metabolites 5-hydroxy- and N4-acetyl-5-hydroxysulphamethoxazole are not glucuronidated. N4-acetylsulphamethoxazole is neither deacetylated nor hydroxylated.

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