Abstract
The Ni-Fe-S proteins carbon monoxide dehydrogenase (COdH) and acetyl coenzyme A synthase (ACS) are enzymes crucial to the global carbon cycle, as they interconvert C1 entities, CO2, CO, and CH3equivalent, via redox reactions that allow certain archae and eubacteria to grow autotrophically, fixing CO2 via the Wood–Ljungdahl pathway for their anabolic metabolism [1]. The ancestry of the organisms may be traced to the time of the origin of life, with these enzymes representing Nature’s earliest catalysts [2]. The redox reactions promoted by COdH and ACS, Eqs. 1 and 2, are reminiscent of the industrial water-gas shift and Monsanto acetic acid synthesis reactions, respectively, that may serve to connect the biological and organometallic communities while expanding the bioorganometallic paradigm beyond B12 chemistry [3]: COþH2O CO2 þ 2Hþ þ 2e ð1Þ
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
