Abstract
Summary The specific activity (activity/mg protein) of three enzymes has been measured in the distal segment of the rat sciatic nerve during Wallerian degeneration obtained by complete nerve transection. The three enzymes are acetyl-CoA synthetase, NADP malate dehydrogenase and ATP citrate lyase. It has been found that the specific activity of all the three enzymes undergoes an early increase followed by a fast return to normal or subnormal values. An attempt has been made to integrate these findings in the sequential pattern of early enzyme changes which occur in the peripheral nerve of mammals during Wallenrian degeneration.
Published Version
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