Abstract
AbstractA simple and efficient three‐component procedure has been developed for the synthesis of a series of spiro‐isoxazolo[5,4‐b]pyridines/quinolines by one‐pot condensation of isatins, 3‐methylisoxazol‐5‐amine and enolizable cyclic carbonyl compounds. The protocol has been accomplished under solvent‐free conditions by grinding the components at room temperature in presence of catalytic CH3COOH. The described process offers environmentally benign reaction conditions for the synthesis of pharmacologically important spirooxindole fused heterocycles with the advantages ofoperational simplicity, short reaction time and good to excellent yields of isolated pure product.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
