Abstract

SummaryThe present investigation involving p-aminohippurate uptake by rabbit kidney slices has shown (i) confirmative evidence that p-aminohippurate uptake is stimulated by the presence of acetate at both 25 and 37°; (ii) oxygen consumption being stimulated by acetate at 25 but not at 37°; (iii) the Km for p-aminohippurate uptake at 37° is not affected by the presence of acetate in the medium; (iv) the Vmax for p-amino-hippurate uptake at 37° is directly related to the presence of acetate in the medium; and (v) acetate stimulates ATP utilization at 37° but does not alter energy charge potential.

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