Abstract
If the extrahepatic metabolism of acetaldehyde in humans is similar to that which occurs in rats (1-6), venous blood acetaldehyde concentrations may not reflect those in potentially sensitive organs such as the brain. It is important to obtain estimates of the levels of acetaldehyde in blood (a) leaving the liver, in order to determine the maximum toxic potential of acetaldehyde, and (b) presented to the brain, since current theories proposing a role for acetaldehyde in the development of addiction to ethanol involve its interaction with components of the central nervous system (7,8).KeywordsPeripheral Venous BloodPartition RatioAcetaldehyde LevelBlood Ethanol ConcentrationHepatic Venous BloodThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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