ACE-it: a tool for genome-wide integration of gene dosage and RNA expression data

Abstract

We describe a tool, called ACE-it (Array CGH Expression integration tool). ACE-it links the chromosomal position of the gene dosage measured by array CGH to the genes measured by the expression array. ACE-it uses this link to statistically test whether gene dosage affects RNA expression. ACE-it is freely available at http://ibivu.cs.vu.nl/programs/acewww/.