Abstract

The angiotensin-converting enzyme (ACE) gene carries two alleles: insertion (I) and deletion (D) polymorphism inside its intron 16 . The study investigation the association between genetic polymorphisms and prostate patients. Materials and Methods: 75 prostate cancer patients, 75 prostate benign and 81 healthy were included. The ACE I/D genotypes were determined by PCR (polymerase chain reaction) Results showed for ACE gene polymorphism at that DD allele relation with prostate cancer p-value 0.0001** and prostate benign relation with ID allele p-value 0.0097**. This study aimed to detecting genetic early marker in angiotensin I converting enzyme (ACE) gene Iraqi patients with prostate carcinoma.

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