Abstract
Small-animal imaging has become an important technique for the development of new radiotracers, drugs and therapies. Many laboratories have now a combination of different small-animal imaging systems, which are being used by biologists, pharmacists, medical doctors and physicists. The aim of this paper is to give an overview of the important factors in the design of a small animal, nuclear medicine and imaging experiment. Different experts summarize one specific aspect important for a good design of a small-animal experiment.
Highlights
The European Association of Nuclear Medicine (EANM) symposium entitled Preclinical Imaging: Systems, Acceptance Testing and Implementation and Practical Issues was set up to bring experts from different backgrounds together and summarizes the most important aspects affecting the quality in small-animal imaging experiments with a focus on molecular imaging with PET, SPECT and CT [1, 2]
We summarize in a concise manner the most important aspects of animal imaging for a general scientific public
To minimize the failure of often expensive studies, it is important to attribute sufficient attention to each of the aspects described in this paper
Summary
The European Association of Nuclear Medicine (EANM) symposium entitled Preclinical Imaging: Systems, Acceptance Testing and Implementation and Practical Issues was set up to bring experts from different backgrounds (animal models, handling, quality control and imaging systems) together and summarizes the most important aspects affecting the quality in small-animal imaging experiments with a focus on molecular imaging with PET, SPECT and CT [1, 2]. In this white paper, we summarize in a concise manner the most important aspects of animal imaging for a general scientific public.
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