Abstract
Abstract Objectives: To examine the accuracy of waist circumference to predict two or more metabolic syndrome (MS) components among the elderly and to compare it with the recommendations of the Joint Interim Statement (JIS) for adults. Method: The study was conducted among participants of the baseline of the Bambuí (Minas Gerais) Cohort Study. The best waist circumference cut-off point for the outcome was determined by the Younden Index. The accuracy of such cut-off points was assessed by the area under the ROC curve (AUROC) and the sensitivity, specificity and positive and negative predictive values. Results: The prevalence of MS was 63.8% among women and 43.4% among men. Of these, the waist circumference cut-off that best predicted two or more components of MS (≥88 cm) was similar to that recommended by JIS (≥90 cm) (AUROC=0.673 and 0.672, respectively). Among women, the corresponding value was higher (≥92 cm) than recommended by the JIS (≥80 cm) (AUROC=0.605 and 0.560, respectively). Conclusion: The overall accuracy of waist circumference (AUROC) for the outcome was low for both genders, indicating that this measure is not an effective predictor of other components of MS in the study population.
Highlights
Participants signed an Informed Consent Term for all the study procedures.Metabolic Syndrome (MS) is a complex disorder represented by a set of factors related to central fat deposition and insulin resistance
As it is an obtainable measure, waist circumference can be used for tracking other factors that make up metabolic syndrome (MS), the assessment of which depends on biochemical and blood pressure measurements
Considering the different values found in these studies, new investigations among different populations are required to determine cutoff points that may be useful in predicting the other components of MS among elderly individuals
Summary
Participants signed an Informed Consent Term for all the study procedures. Metabolic Syndrome (MS) is a complex disorder represented by a set of factors related to central fat deposition and insulin resistance. A Joint Interim Statement ( JIS)[3] was issued, which adopted cutoff points for the circumference of more sensitive waists, which is not essential for the diagnosis of the syndrome. While these criteria are recommended for the adult population, there is no specific recommendation for the elderly population. The present study aimed to determine the waist circumference cut-off points for the prediction of two or more components of MS in a large population base of elderly men and women, and to compare them with the corresponding values of the JIS3 recommendations for adults. The use of medications was evaluated through a face-to-face interview, and the prescriptions and/or packaging of drugs consumed were requested
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