Abstract
BackgroundTo evaluate the accuracy of biometric measurements by a swept-source optical coherence tomography (SS–OCT) based biometry for intraocular lens (IOL) power calculation.MethodsThis retrospective observational study enrolled 431 patients undergoing cataract surgery. The charts were reviewed to investigate the failure rate of axial length (AL) measurement of the SS–OCT biometer, partial coherence interferometry (PCI), and A–scan ultrasonography (US) according to cataract type and severity. AL and keratometry in 164 eyes with the same IOL inserted were measured using the SS–OCT biometer, PCI, and A–scan US. The SRK/T formula was used to calculate IOL power. The mean absolute error (MAE) and percentage of eyes with a prediction error (PE) of ±0.50 D were compared.ResultsThe AL measurement failure rate was 0.00% for A–scan US, 2.32% for the SS–OCT biometer, and 15.31% for PCI. The number of eyes measured using three devices (SS–OCT biometer, PCI, and A–scan US) was 128 (Group A) and the number of eyes measured using two devices (SS–OCT biometer and A–scan US) was 36 (Group B). The score of posterior subcapsular opacity was significantly different between two groups (p < .001). The SS–OCT biometer and PCI showed significantly lower MAE compared to A–scan US in Group A (p = 0.027). Using SS-OCT biometer, MAE showed no significant difference between Group A (0.36 ± 0.27) and Group B (0.36 ± 0.31) (p = 0.785). Whereas, MAE of A-scan US was significantly higher than Group A (0.47 ± 0.39) in Group B (0.64 ± 0.36) (p = 0.023).ConclusionsUsing biometry with advanced OCT is useful in clinical practice as it is more effective in obtaining biometric measurements in the eyes with PSC and provides accurate measurements for IOL power calculation regardless of cataract type and severity.Trial registrationRetrospectively registered. Registration number: KC16RISI1020. Registered 03 January 2018.
Highlights
To evaluate the accuracy of biometric measurements by a swept-source optical coherence tomography (SS–OCT) based biometry for intraocular lens (IOL) power calculation
The swept source (SS)–OCT biometer showed comparable mean absolute error (MAE) in Group A (0.36 ± 0.27) and Group B (0.36 ± 0.31), while the A-scan US showed a greater MAE in Group B (0.64 ± 0.36) than Group A (0.47 ± 0.39). These results suggest high accuracy of SS–OCT technology in posterior subcapsular cataract (PSC) as well as normal density cataracts
partial coherence interferometry (PCI) has been regarded as an excellent noncontact measurement method in the eyes of cataract patients
Summary
To evaluate the accuracy of biometric measurements by a swept-source optical coherence tomography (SS–OCT) based biometry for intraocular lens (IOL) power calculation. In the era of refractive cataract surgery, the achievement of a desired refractive outcome begins with intraocular lens (IOL) power calculation based on accurate biometry. The refractive status after cataract surgery is affected by various factors such as measurement error of the axial length (AL), measurement error of the corneal power, and the estimation of the pseudophakic anterior chamber depth (ACD) [1]. AL measurement accounts for 54% of the sources causing error in the refractive outcome in cataract surgery [1]. Lenstar LS 900 provides measurements of AL, keratometry (K), anterior chamber depth, and white-to-white, as well as central corneal thickness, pupil size, and lens thickness [4]. Accurate measurement of AL in patients with posterior subcapsular cataract (PSC) remains a challenge [5]
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