Accuracy of SS-OCT biometry compared with partial coherence interferometry biometry for combined phacovitrectomy with internal limiting membrane peeling

Abstract

To evaluate the accuracy of a swept-source optical coherence tomography (SS-OCT) biometer compared with a standard partial coherence interferometry (PCI) biometer in terms of phacovitrectomy for vitreomacular pathology and cataract. Department of Ophthalmology, Ludwig-Maximilians-University Munich, Germany. Prospective, nonrandomized, single center consecutive case series. Patients with age-related cataract, regular corneal astigmatism less than 1.25 diopters (D) and a clinically significant vitreomacular pathology (epiretinal membrane [ERM], macular hole, or vitreomacular traction [VMT] syndrome) who had combined phacovitrectomy with internal limiting membrane peeling were enrolled. Objective and manifest refraction, corrected distance visual acuity, SS-OCT biometry, and PCI biometry were obtained preoperatively and 3months postoperatively. The refractive prediction error and mean absolute error (MAE) were calculated for each biometric device with the Haigis formula. The percentage of eyes with a prediction error within ±0.50 D or less were calculated. The study comprised 79 eyes of 79 patients. The mean refractive prediction error of all eyes was -0.27 D ± 0.76 (SD) for the PCI biometer and -0.28±0.57 D for theSS-OCT biometer (P=.802), and the MAE was 0.61±0.53D and 0.46±0.43 D, respectively (P=.012). A prediction error within ±0.50 D or less was observed in 55 eyes (70%) with the SS-OCT biometer compared with 42 eyes (53%) with the PCI biometer (P=.0001). The MAE with the SS-OCT biometer was statistically significantly lower in eyes with ERMs or macular holes compared with the PCI biometer (P=.043 and P=.028, respectively), whereas no statistically significant difference was observed in eyes with VMT syndrome (P=.286). The SS-OCT biometer showed a statistically significant lower MAE compared with the PCI biometer, and it is recommended for precise intraocular lens power calculations in combined phacovitrectomy for cataract and vitreomacular diseases.