Accuracy of guided biopsy of the jawbone in a clinical setting: A retrospective analysis

Martin Lotz,Caterina Schumacher,Bernd Stadlinger,Kristian Ikenberg,Martin Rücker,Silvio Valdec

doi:10.1016/j.jcms.2021.02.025

Martin Lotz, Caterina Schumacher + Show 4 more

Open Access

https://doi.org/10.1016/j.jcms.2021.02.025

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Abstract

The aim of this study was to investigate the accuracy of a previously described technique for guided biopsy of osseous pathologies of the jawbone in a clinical setting. The data sets of patients who had undergone guided biopsy procedures were retrospectively examined for accuracy. Digital planning of the biopsies and manufacturing of the tooth-supported drilling template were performed with superimposed cone beam computed tomography and intraoral scans using implant planning software. After a trephine biopsy was taken using the template, the postoperative low-dose cone beam computed tomography was analyzed for accuracy using the planning software with the corresponding (digitally-planned) biopsy cylinder. The mean angular deviation was 4.35 ± 2.5°. The mean depth deviation was −1.40 ± 1.41 mm. Guided biopsy seems to be an alternative to a conventional approach for minimally invasive and highly accurate jawbone biopsy.

Highlights

In medicine and dentistry, the progress of digitalization introduces new treatment options, and a higher degree of safety and predictability (Coravos et al, 2019)
Irregularities in the jawbone are often accidently found on radiological scans, but in most cases a histopathological examination is required to make a reliable diagnosis
These osseous lesions form a heterogeneous group of disorders, but their appearances are similar (Slootweg, 1996)

Summary

Introduction

The progress of digitalization introduces new treatment options, and a higher degree of safety and predictability (Coravos et al, 2019). Today’s 3-dimensional (3D) imaging, such as cone beam computed tomography (CBCT) and dental scans, can be combined with the knowledge of modern guided implantology to integrate safe and minimally invasive guided bone biopsies into the clinical routine. This method enables challenging bone biopsies to be performed under local anesthesia in a predictable manner, reducing both the risks and the invasiveness (Valdec et al, 2019). The aim of this retrospective clinical analysis was to examine the accuracy of template-guided biopsies; the results will guide our recommendations regarding the applicability and adaptation of the method for clinical routines and further procedures

Materials and methods

Accuracy analysis

Digital planning

Surgery

Statistical analysis

Discussion