Abstract

Background: Breast cancer is the first one among Iraqi females. Most of them present later for diagnosis. Early detection center in tertiary hospital practice uses FNAB for early diagnosis. Publications on accuracy of this detection are scarce.
 Objective: To test the accuracy of FNAB in breast lump diagnosis.
 Methods: Diagnostic test accuracy study, on 204 women with breast lump, attending the oncology department in 2017.
 Results: Fine-needle aspiration biopsy diagnosis of histologically malignant cases were, malignant in 89 (87.3%), suspicious of malignancy in 5 (4.9%), and benign in 4 (3.9%). Complete sensitivity was 87.3%, and specificity was 100%, with 12.7% false negative results and no false positive cases. The accuracy was 94%.

Highlights

  • Breast cancer is commonest cancer among women, comprising about 23% of the newly diagnosed cancers among females, and 6 % of all deaths worldwide [1,2] .In Iraq, female incidence rate was 23.01 per100,000, accounting about 34% of all reported cancer among females [3]

  • 6 Ultrasound guided fine-needle aspiration biopsy (FNAB) has been widely used for non-palpable breast lumps.[7,8] core biopsy is preferred to FNAB in most developed countries, its procedure is more expensive and time consuming as compared to FNAB [9]

  • Accuracy of FNAB was done by sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV)

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Summary

Introduction

Breast cancer is commonest cancer among women, comprising about 23% of the newly diagnosed cancers among females, and 6 % of all deaths worldwide [1,2] .In Iraq, female incidence rate was 23.01 per100,000, accounting about 34% of all reported cancer among females [3]. Breast cancer survival rates tend to be poor in developing countries, most likely because of a combination of late diagnosis and limited access to timely and appropriate treatment [4] . 6 Ultrasound guided FNAB has been widely used for non-palpable breast lumps.[7,8] core biopsy is preferred to FNAB in most developed countries, its procedure is more expensive and time consuming as compared to FNAB [9] . A population based breast cancer screening program is not established in Iraq and only early detection centers, and clinics, were established at tertiary hospitals 12 .

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