Abstract

FDG PET-CT is an established tool for response assessment following definitive concurrent chemoradiotherapy for head and neck squamous cell carcinoma with a high negative predictive value guiding treatment decisions. Little data is available regarding the accuracy of FDG PET-CT for response assessment following definitive radiotherapy without chemotherapy. We retrospectively analysed the accuracy of FDG PET-CT for response assessment following radiotherapy alone without planned neck dissection in 45 patients. PET-CT had a high negative predictive value of 93% and positive predictive value of 88%. Based upon the high negative predictive value, PET-CT can be used to avoid surgical intervention following radiotherapy alone.

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