Abstract
In 2008, human granulocytic anaplasmosis (HGA) was reported from China. However, the clinical and laboratory findings, including reports of nosocomial transmission, were inconsistent with those reported for HGA in the United States. In 2012, it was demonstrated that the patients described in the 2008 report had all been infected with a newly discovered bunyavirus, severe fever with thrombocytopenia syndrome virus, which causes an illness with the same clinical features described for the patients in the 2008 report. This finding raises the question of HGA misdiagnosis in China and establishes the need for further studies to determine whether HGA occurs there.
Highlights
In 2008, human granulocytic anaplasmosis (HGA) was reported from China
To determine the accuracy of the report from China, I compared certain clinical and laboratory features of the 9 laboratory-confirmed cases of HGA in that outbreak [1] with 44 culture-confirmed cases of HGA reported from a study conducted in the United States [4] (Table 1)
As was pointed out in the editorial that accompanied the report of HGA in China [5], other noteworthy differences were observed between the HGA patients in China and those in the United States
Summary
In 2008, human granulocytic anaplasmosis (HGA) was reported from China. the clinical and laboratory findings, including reports of nosocomial transmission, were inconsistent with those reported for HGA in the United States. To determine the accuracy of the report from China, I compared certain clinical and laboratory features of the 9 laboratory-confirmed cases of HGA in that outbreak (all secondary case-patients were claimed to have been infected by the index patient) [1] with 44 culture-confirmed cases of HGA reported from a study conducted in the United States [4] (Table 1). One of these differences was relative bradycardia in all 9 patients in China [1], a finding never reported for HGA in the United States.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
