Abstract
Background: Malignant liver mass, especially hepatocellular carcinoma (HCC), is the most common primary malignant tumour of the liver representing more than 80% of all primary hepatic malignancies.
 Methods: This cross sectional study was carried out in the Department of Radiology. All the clinically suspected patients having hepatic mass at any age with both sexes who were attended in hospital were taken as study population as per inclusion and exclusion criteria. Patients having hepatomegaly due to extra hepatic causes, patients who refused to undergo CT-scan, patients who refuse to do biopsy or whose biopsy result was not available and patients having known hypersensitivity reaction to contrast agent were excluded from this study.
 Results: Sensitivity of CT to diagnose malignant lesion was 94.12%, specificity 84.62%, accuracy 90%, positive predictive value 88.89% and negative predictive value 91.67%.
 Conclusion: The results of the present study therefore conclude that CT is a useful modality for the diagnosis of malignant liver masses. Since the CT diagnosis correlates with histopathological connection, it is a sensitive modality on the basis of the above findings.
 Keywords: Test accuracy, CT-Scan, Malignant, Liver Mass
Highlights
Background: Malignant liver mass, especially hepatocellular carcinoma (HCC), is the most common primary malignant tumour of the liver representing more than 80% of all primary hepatic malignancies
The results of the present study conclude that CT is a useful modality for the diagnosis of malignant liver masses
On CT-scan, HCC appears as low density lesions as these are supplied mainly by arterial blood rather than portal venous blood and insufficient blood flow in the hepatic artery contributes to necrosis of hepatic tissue and to further lowering of the density of CT-scan
Summary
Especially hepatocellular carcinoma (HCC), is the most common primary malignant tumour of the liver representing more than 80% of all primary hepatic malignancies. It is relatively common in equatorial Africa and Asia, rare in United States. On CT-scan, HCC appears as low density lesions as these are supplied mainly by arterial blood rather than portal venous blood and insufficient blood flow in the hepatic artery contributes to necrosis of hepatic tissue and to further lowering of the density of CT-scan. With the exception of some hepatic lesions containing calcium, extravasated blood, fat or densely enhanced parts, the CT-scan appearance of liver tumours is similar and nonspecific regardless of their histologic type. Hepatocellular adenoma is the most common benign liver tumours. The present study was designed to evaluate the role of CT-scan in the evaluation of malignant hepatic mass and was correlated with histopathology
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More From: International Journal of Medical and Biomedical Studies
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