Accuracy of a prototype dark blood late gadolinium enhancement technique for the detection and quantification of myocardial infarction

Akos Varga-Szemes,Julian L Wichmann,Uwe Joseph Schoepf,Stefanie Mangold,Damiano Caruso,Stephen R Fuller,Pal Suranyi,Carlo N De Cecco,Wolfgang G Rehwald,Sheldon E Litwin,Giuseppe Muscogiuri

doi:10.1186/1532-429x-18-s1-q65

Abstract

Background Conventional inversion recovery (IR) techniques for the detection of late gadolinium enhancement (LGE) in the myocardium are bright blood methods in which the signal in the blood chamber is often similar to the signal in hyperenhanced irreversibly damaged myocardial areas. Due to the low contrast to noise ratio (CNR) between blood and the hyperenhanced myocardium at the tissue-blood interface, the discrimination of subendocardial LGE from blood is often challenging with this approach. The aim of our study was to evaluate the accuracy of a prototype dark blood LGE technique for the detection and quantification of myocardial LGE in patients with myocardial infarction (MI) when compared to conventional IR LGE technique.

Highlights

Conventional inversion recovery (IR) techniques for the detection of late gadolinium enhancement (LGE) in the myocardium are bright blood methods in which the signal in the blood chamber is often similar to the signal in hyperenhanced irreversibly damaged myocardial areas
Due to the low contrast to noise ratio (CNR) between blood and the hyperenhanced myocardium at the tissue-blood interface, the discrimination of subendocardial LGE from blood is often challenging with this approach
The aim of our study was to evaluate the accuracy of a prototype dark blood LGE technique for the detection and quantification of myocardial LGE in patients with myocardial infarction (MI) when compared to conventional IR LGE technique

Summary

Introduction

Conventional inversion recovery (IR) techniques for the detection of late gadolinium enhancement (LGE) in the myocardium are bright blood methods in which the signal in the blood chamber is often similar to the signal in hyperenhanced irreversibly damaged myocardial areas. Due to the low contrast to noise ratio (CNR) between blood and the hyperenhanced myocardium at the tissue-blood interface, the discrimination of subendocardial LGE from blood is often challenging with this approach. The aim of our study was to evaluate the accuracy of a prototype dark blood LGE technique for the detection and quantification of myocardial LGE in patients with myocardial infarction (MI) when compared to conventional IR LGE technique

Objectives

Methods

Results

Conclusion