Abstract
BackgroundAdnexal cancers are in fifth place among the tumors with the highest mortality in the female population. The aim of the present study was to evaluate the accuracy of Multi-detector computed tomography (MDCT) on a 64-multislice CT scanner in the detection and differentiation of adnexal masses stages.MethodsDuring the present prospective study, 95 women with a primary diagnosis of ovarian mass in base of clinical examination and ultrasonographic findings underwent preoperative evaluation by a 64-slice MDCT with a section thickness of 0.6 mm, 50% overlap and reconstructed images. Afterward, results of MDCT were compared with surgical and histopathological findings, and the sensitivity, specificity, positive and negative predictive value and accuracy were determined.ResultsThe mean age of patients was 48.63 ± 13.93 years. MDCT diagnosed 25 (26.3%) masses to be benign and 70 (73.7%) to be malignant (sensitivity, specificity, positive and negative predictive value and accuracy were 92.8%, 88.0%, 95.5%, 81.4% and 91.5% respectively). The sensitivity and specificity of MDCT in determining local extension was 72.2% and 93.4% respectively. And the sensitivity and specificity of MDCT in determining peritoneal seeding and liver extension was 81.8% and 93% respectively. Estimated stage was significantly agreed with the surgical (Cohen's Kappa (κ) = 0.891) and histopathological findings (κ = 0.858).ConclusionMDCT is a highly sensitive and specific diagnostic method in evaluation of adnexal masses and successfully stage the tumor in consistent with surgery and histopathology.
Highlights
Adnexal cancers are in fifth place among the tumors with the highest mortality in the female population
The diagnostic accuracy of spiral Computed tomography (CT) and its axial views for nature and extension of the adnexal masses were reported [13], the present study aimed to evaluate the accuracy of 64-multidetector computed tomography in detection, differentiation and staging of adnexal tumors
The sensitivity, specificity, positive and negative predictive value and accuracy of Multi-detector computed tomography (MDCT) for diagnosing a malignant mass was 92.8%, 88.0%, 95.5%, 81.4% and 91.5% respectively comparing to histopathological evaluation of the specimens (Figure 2)
Summary
Adnexal cancers are in fifth place among the tumors with the highest mortality in the female population. The aim of the present study was to evaluate the accuracy of Multi-detector computed tomography (MDCT) on a 64-multislice CT scanner in the detection and differentiation of adnexal masses stages. Malignancies of the female reproductive system are among serious causes of mortality and morbidity, and adnexal cancers are in fifth place among the tumors with the highest mortality in the female population [1]. Computed tomography (CT) has been used primarily in patients with ovarian malignancies to reveal the stage of tumor, detect persistent or recurrent disease and demonstrate tumor response to therapeutic approach [9,10]
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