Abstract
σ-Aminolevulinic acid and phenanthroline induced accumulation of metal-free porphyrins in homogenates of thyroid tissue and cells obtained after thyroidectomy. The rate of pigment synthesis considerably increased in specimens isolated from pathologically changed tissue, and the pigments were primarily located in cells. The results indicate that endogenous porphyrins can be used in the diagnosis and phototherapy of thyroid tumors.
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