Abstract

The American College of Clinical Pharmacology (ACCP) has published a “Drugs of Abuse” supplement for its Journal of Clinical Pharmacology. Covering all substances from tobacco and alcohol to prescription and illicit drugs, the supplement is designed to fill in clinical trial gaps with mechanistic insight to allow clinicians to better assess and treat complex patients,” according to the editors. “Primary care, psychiatric, toxicological and emergency/critical care clinicians will all benefit from understanding how these substances of abuse cause their pharmacologic effects and how best to counteract it.” The co‐editors for the supplement (Drs. C. Michael White and Anne Nafziger) jointly stated, “We see many instances where clinicians are confused about why patients experience the effects they do from substances of abuse and how best to care for them. We wanted to draw the combined wisdom of international experts in clinical pharmacology to break down the pharmacologic and pharmacokinetic underpinnings for why these effects occur, the time course for these effects and why there is variability in response.” For the supplement, go to https://accp1.onlinelibrary.wiley.com/toc/15524604/2021/61/S2.

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