Abstract
Accidental opioid intoxication in children is a rare affection in morocco, its recognition and management must be immediate to avoid its life threatening complications. In a period of two years (September 2019 - September 2021), two cases of severe opioid intoxication in children have been admitted in the intensive care department of the children’s hospital of Rabat. The first case is a 9 years old child admitted for tonic-clonic seizures with acute respiratory distress due to Fentanyl intoxication after being exposed to a skin patch dosed 75 μg/hour, he required mechanical ventilation and was treated with a bolus of 0,8 mg of Naloxone completed with continuous infusion for 48 hours with favorable evolution and hospital release in 5 days. The second case is a 2 years 5 months old child admitted for decreased consciousness with bradypnea due to morphine intoxication after oral ingestion of 5 extended-release morphine tablets dosed 30 mg each, treated with a single bolus of 0,8 mg of Naloxone with rapid improvement.
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