Abstract
Accidental and Surreptitious Intake of Oral Anticoagulants Including Older and Newer Agents - A Diagnostic Dilemma
Highlights
Even with newer oral anticoagulants (NOACs) like dabigatran, with proper monitoring and changing the dose as needed, major bleeds could be reduced by 30-40% in comparison and the upper and lower GI endoscopies were reported unremarkable
Diltiazem increases plasma levels of apixaban by 40%, another NOAC
Diltiazem increased 40% of plasma levels of apixaban [12]. Routine coagulation tests such as PT and APTT are not ideal to measure NOACs, as the reagents used vary in sensitivity to thrombin and factor Xa inhibitors [13,14]
Summary
In February 2016 patient was readmitted again with vaginal and rectal bleeding (in between she has had inpatient care at other hospitals in the State of Florida). This time the gastroenterologist who did the sigmoidoscopy noted crusted blood in the mucosal fold (prior to any treatment with blood products). We report a 62-year-old Caucasian female working in attorney’s office presenting with gross vaginal and rectal bleeding. Her previous history is significant for morbid obesity for which she has had Rouxen-Y gastric bypass surgery in 2007.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
