Abstract
Lopez Hernandez MA1* and Lopez De Lucio S2 Author Affiliations 1HIV Clinic, General Regional Hospital Nª1, Mexico 2Cerrada de Yalai Mz2 L2 C 148, Palmas 2, Ixtapaluca, Mexico Received: October 21, 2020| Published: October 30, 2020 Corresponding author: Lopez Hernandez MA, HIV Clinic, General Regional Hospital Nª1, Mexico DOI: 10.26717/BJSTR.2020.31.005120
Highlights
Primate immunodeficiency viruses, including human immunodeficiency virus type 1 (HIV-1), The presence of accessory genes are characteristic of them, such as vif, vpr, vpx, vpu, and nef
When the human immunodeficiency virus type 1 was cloned and sequenced for first time, the researchers were surprised to find that this virus contained several additional open reading frames. in addition to the prototypical retroviral gag, pol, and env genes; Collectively, they were termed accessory genes due to a lack of understanding of their biological functions
Virus protein U or Vpu is a lentiviral viroporin of 81 aminoacid, that is specific of HIV-1.This accessory protein is a membrane phosphoprotein, oligomeric with diversified biological functions
Summary
Citation: Lopez Hernandez MA, Lopez De Lucio S. Accessory Regulatory Proteins of HIV-1 and Host Restriction Factors Interactions. Biomed J Sci & Tech Res 31(4)-2020. BJSTR. MS.ID.005120. Keywords: HIV-1 Accessory Proteins; Restriction Factors; APOBEG3G; BST2; SERINC5; SERINC3; Vif; Vpu; Nef; Vpr
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