Abstract

AbstractAn atom‐economical approach for the synthesis of 3‐aminofurans/thiophenes via a conjugate addition of alcohols and thiols with electron withdrawing groups (EWGs) at α positions on alkynenitriles followed by a modified Thorpe‐Ziegler cyclization have been reported. This operationally simple protocol offers a rapid access to a library of 3‐aminofurans/thiophenes in moderate to good yields.magnified image

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