Abstract

In this retrospective cohort study, we describe acceptability, tolerability and potential efficacy of cognitive behavioural therapy (CBT) in Insomnia Disorder subtypes, derived from polysomnography (PSG): insomnia with normal-sleep duration (I-NSD) and insomnia with short-sleep duration (I-SSD). All research volunteers were offered access to digital CBT, single component sleep restriction therapy and face-to-face group CBT. Follow-up occurred at three months post-treatment using the insomnia severity index (ISI). 96 participants (61 females, mean age of 41 years) were grouped into either normal-sleep (n = 53) or short-sleep (n = 43). CBT was acceptable to 63% of participants (normal-sleep = 31, short-sleep = 29), with 28 completing therapy (tolerability: normal-sleep = 11, short-sleep = 17). For potential efficacy, 39 (normal-sleep = 20, short-sleep = 19) out of 96 participants (41%) completed a follow-up ISI assessment. In this reduced sample, mean (SD) ISI scores decreased across both groups (normal-sleep: 18.0 (4.0) to 10.7 (4.6); short-sleep: 16.5 (5.5) to 11.0 (6.3); both P < 0.01). Those with normal-sleep were more likely to respond (≥6-point ISI reduction) to CBT compared to short-sleep (70%, n = 14/20 vs. 37%, n = 7/19 respectively, P = 0.038). In this cohort, 60 (63%) of participants attempted CBT and of those 28 (47%) completed therapy. Results may be comparable to clinical participants with implications for the successful translation of CBT for insomnia.

Highlights

  • Insomnia is a common and distressing disorder that impairs quality of life and affects approximately 6 to 10% of the adult population1,2

  • It has been proposed that this phenotype is clinically useful as participants may not respond as well to cognitive behavioural therapy (CBT) treatment compared to participants with insomnia and more normal-sleep duration insomnia (>6 hours TST)10

  • We hypothesized that insomnia with short-sleep duration (I-SSD) participants would have higher insomnia severity index (ISI) scores at follow-up with lower ISI response and remission rates compared to participants with insomnia with normal-sleep duration (I-NSD)

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Summary

Introduction

Insomnia is a common and distressing disorder that impairs quality of life and affects approximately 6 to 10% of the adult population. Other researchers found an attenuated treatment response in participants (n = 35 I-SSD; n = 25 I-NSD) with

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