Abstract
Accelerated stability studies were carried out on Glinus lotoides L. tablets for six months following the guidelines of International Conference on Harmonization (ICH) and European Agency for the Evaluation of Medicinal Products (EMEA) at 40 + 2 oC and 75 + 5% relative humidity (RH). A group of colour forming compounds was used as marker substances of Glinus lotoidesextract. Quantification of the active components i.e., saponins of G. lotoideswas carried out by colourimetric analytical procedure. Physical properties of tablets, assay of colour forming compounds, and TLC profiles were used as parameters to study the stability. The results obtained indicated that optimized G. lotoidestablets were stable, as evidenced by the absence of significant changes in their physical properties, assay and TLC profiles. Keywords: accelerated stability, Glinus lotoides tablets, ICH guidelines, EMEA guidelines, colourimetric assay Ethiopian Pharmaceutical Journal Vol. 25 (1) 2007: pp. 43-50
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
