Abstract
Background Delayed contrast enhancement (DCE) imaging is a well-established MRI technique for the evaluation of myocardial infarction (MI) and tissue viability [1]. Inversion-recovery (IR) is used to visualize the hyperenhanced regions of scar after injection of Gd-DTPA. Mid-diastolic segmented k-space coverage is typical, requiring several heartbeats to reconstruct an image [2]. More recently, Cartesian single-shot trueFISP imaging,[3] has achieved free-breathing acquisitions though spatial resolution is traded for imaging speed and multiple heartbeats may be needed to increase SNR through averaging [4]. Alternatively, radial imaging can achieve higher degrees of acceleration[5], and should produce sharper images in patients with high heart-rates and with shorter or non-existent quiescent periods. We demonstrate the feasibility of IR-DCE imaging with a rapid radial sequence accelerated using through-time radial GRAPPA with and without multiheartbeat averaging.
Highlights
Delayed contrast enhancement (DCE) imaging is a well-established MRI technique for the evaluation of myocardial infarction (MI) and tissue viability [1]
Images captured in single heartbeats were compared to images reconstructed after k-space averaging (8 heartbeats)
Images from single heartbeats are noisier compared to those that are averaged over heartbeats, though the infarct is still visible and welldelineated
Summary
Delayed contrast enhancement (DCE) imaging is a well-established MRI technique for the evaluation of myocardial infarction (MI) and tissue viability [1]. Through-time radial GRAPPA [5] was used to reconstruct 1.56 × 1.56 mm2 resolution images. For calibration of the weights, 80 fully-sampled (128 spokes) frames were acquired prior to infusion of contrast.
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