Accelerated Brain Atrophy and Changes in White Matter Diffusivity are Associated With Mortality, Declining Health, and Declining Cognitive Functioning Among Homeless and Precariously Housed Individuals: A Longitudinal Study

Jacob Stubbs,Andrea Jones,Kristina Gicas,Alexandra Vertinsky,Manraj Heran,Wayne Su,Breanna Nelson,Donna Lang,Thalia Field,Allen Thornton,Alasdair Barr,Olga Leonova,William Macewan,Alexander Rauscher,William Honer,William Panenka

doi:10.1016/j.biopsych.2022.02.221

Accelerated Brain Atrophy and Changes in White Matter Diffusivity are Associated With Mortality, Declining Health, and Declining Cognitive Functioning Among Homeless and Precariously Housed Individuals: A Longitudinal Study

Jacob Stubbs, Andrea Jones + Show 14 more

https://doi.org/10.1016/j.biopsych.2022.02.221

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Journal: Biological psychiatry

Publication Date: Apr 28, 2022

Affiliation: University of British Columbia, York University, Simon Fraser University

#Accelerated Brain Atrophy #White Matter Diffusivity + Show 8 more

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Abstract

Individuals who are homeless or precariously housed experience poorer health and earlier mortality compared to the general population. We evaluated longitudinal changes in quantitative MRI measures of brain structure, and how these changes are related to mortality, and change in health and functioning.

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