Acanthamoeba Keratitis Following Keratoplasty Without Other Identifiable Risk Factors

Abstract

Acanthamoeba keratitis, most frequently occurring in the setting of contact lens wear, has been widely documented over the past several years. We encountered a case of Acanthamoeba keratitis following penetrating keratoplasty without other identifiable risk factors. Report of a Case. —A 74-year-old white woman underwent penetrating keratoplasty in her right eye for bullous keratopathy. She was referred 6 months later for evaluation of a retrocorneal membrane and glaucoma. Examination revealed a retained Descemet's membrane, stromal edema, epithelial haze, and punctate epithelial erosions in the right eye. Repeated penetrating keratoplasty with extracapsular cataract extraction and posterior chamber intraocular lens was subsequently performed by the referring physician. Three weeks after surgery, the patient developed an inferior stromal keratitis, epithelial defect, and hypopyon in the right eye and was referred for management. See also p 463. Results of anterior chamber and vitreous taps and corneal cultures were negative for organisms, as was subsequent