Abstract
Prescription drugs have enormous potential to improve health and longevity, and the past decades have witnessed remarkable innovations in the pharmaceutical marketplace. Despite this, the past decades are also replete with examples of therapies, ranging from thalidomide to rofecoxib to sibutramine, that have raised important safety concerns. The recent outbreak of fungal meningitis linked to unsterile practices at a compounding pharmacy serves as yet another cautionary tale that all drugs have risks and that drugs are manufactured, produced, delivered, and administered in a complex regulatory and clinical environment.
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