Abstract
Evidence is presented that DINE-1 is a highly abundant miniature inverted-repeat transposable element (MITE) family present in all 12 Drosophila species with whole-genome sequence available.
Highlights
Miniature inverted-repeat transposable elements (MITEs) are non-autonomous DNA-mediated transposable elements (TEs) derived from autonomous TEs
We found that Drosophila interspersed element 1 (DINE-1)-related sequences are highly abundant in all 12 species, and share a similar sequence structure, suggesting that a common mechanism was used for their transposition
Identification and common sequence structure characteristics of DINE-1s in 12 Drosophila species Previously, we discovered that DINE-1 is highly abundant and appears to have experienced a recent transpositional burst in the lineage leading to D. yakuba [23]
Summary
Miniature inverted-repeat transposable elements (MITEs) are non-autonomous DNA-mediated transposable elements (TEs) derived from autonomous TEs. These sequences are mostly transposable elements (TEs) or TE-derived sequences, and they play important roles in the evolution of chromosome organization and genome complexity [8] Based on their mechanism of transposition, TEs can be divided into two classes: class I comprises retrotransposons, which transpose through RNA-mediated mechanisms, and class II comprises transposons, which mobilize through DNA-mediated mechanisms [9,10]. The mobilization of non-autonomous SINEs requires retrotransposase from autonomous LINEs, and these elements co-evolve in a highly species-specific manner [11,12] Another example is the miniature inverted-repeat transposable elements (MITEs) found in many plant genomes. MITEs have been found in several animal genomes, including Caenorhabditis elegans, mosquitoes, fish and humans (reviewed in [14]) Both SINEs and MITEs are highly abundant (usually > 1,000 copies per genome) in many host species across a broad taxonomic range. Because of their high abundance and active movement, and their frequent association with genes [15,16], MITEs have had a significant impact on the evolution and complexity of eukaryotic genomes
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