Abstract

A) Photograph of an endoscope within the abdominal cavity with access to the intra-abdominal organs during transmural endoscopy. B) Photograph of a peripheral branch of the posterior Vagus nerve in a patient undergoing the POEM procedure

Highlights

  • Combined traumatic brain injury (TBI) and hemorrhagic shock (HS) (TBI+HS), is associated with high levels of morbidity and mortality

  • Using within-patient comparisons, we show that percepts evoked by stereotactic electroencephalography (SEEG) electrodes are more focal and can be localized to fingertips more often than those evoked by high density ECoG grid electrodes

  • We explored the ability of electrical trigeminal nerve stimulation (TNS) to mimic the hemodynamic oscillations shown in individuals with high hypovolemia tolerance, and investigated its beneficial effects in a rat model of TBI+HS

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Summary

Introduction

Combined traumatic brain injury (TBI) and hemorrhagic shock (HS) (TBI+HS), is associated with high levels of morbidity and mortality. PhD1,2 1Institute of Bioelectronic Medicine, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, New York, US; 2Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, US Correspondence: Theodoros P.

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