Abstracts from the 7th International Conference for Healthcare and Medical Students (ICHAMS)

doi:10.1186/s12919-018-0157-2

Abstract

Highlights

Adherence to secondary prevention medications following acute coronary syndrome (ACS) is low, standing around 40–75% by various estimates
We suggest two etiopathogenic hypotheses of GB development in these cases: a genetic one, with significance for younger patients, and another one related to epigenetic factors, in the case of elderly patients
Dimerization of pyruvate kinase M2 allows translocation to the nucleus and stabilization HIF1a. This culminates in upregulation of pro-inflammatory cytokines (IL-1β) and downregulation of anti-inflammatory cytokines (IL-10). These experiments hypothesized that excessive inflammation observed in Cystic fibrosis (CF) can be in part attributed to a shift towards IL-1β and away from IL-10, and that this shift can be correlated with CF-ABLE score

Summary

Introduction

Adherence to secondary prevention medications following acute coronary syndrome (ACS) is low, standing around 40–75% by various estimates. Methods A prospective study of 54 patients with TB and HIV co-infection was done We performed a systematic review and meta-analysis assessing effects of lower and higher INR targets on thromboembolism and bleeding risk in patients with mechanical heart valves. Previous studies noted that FKBPL deficient mice demonstrate enhanced angiogenesis and increased inflammation This project examined the role of FKBPL and AD-01 on endothelial barrier function and proinflammatory cytokine release, both of which play an integral role in the pathogenesis of conditions such as stroke, insulin-resistant diabetes and septic shock. This study aims to examine: (1) the prevalence of co-morbidities compared with a general Irish female population (TILDA), (2) the prevalence of co-medications and (3) comedications as a proxy for disease in an Irish national breast cancer cohort. We aim to identify protein biomarkers for psychosis in blood, apolipoproteins

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