Abstract WP203: Stroke Occurrence Is Associated With Abnormal Sleep Duration In The United States

Abstract

Background and Purpose: Inappropriate sleep duration (<7 or >8 hours/night) is associated with cardiovascular events. Given its importance, the new American Heart Association Life’s Essential 8 construct of ideal cardiovascular health includes sleep duration. Yet, studies of sleep duration in relation to stroke are scarce. Our objective was to compare sleep duration among individuals with and without prior stroke in a nationally representative U.S. sample. Methods: Using the National Health and Nutrition Examination Surveys database (2005-2018), individuals >=18 years were identified (n=37,987 without self-reported stroke; n=1,572 with self-reported stroke). Prevalence of normal sleep duration (7-8 hours/night) was compared between persons with and without self-reported history of stroke using the Rao-Scott χ; 2 test. Multinomial logistic regression analysis was used to evaluate the relationship between prior stroke and abnormal sleep before and after adjusting for demographic and clinical variables. Results: Compared to individuals without prior stroke, prevalence of normal sleep duration was lower in individuals with prior stroke (18-44 years: 32% vs 54%; 45-64 years: 47% vs 55%; >=65 years: 45% vs 54%). Factors associated with >8 hours/night sleep included female sex, older age, non-White race, lower education, poverty, and obesity. Factors associated with <7 hours/night sleep were male sex, younger age, Black race, lower education, poverty, and obesity. Compared to individuals without stroke, those with prior stroke were more likely to report >8 hours/night (unadjusted OR 2.03, 95% CI 1.64-2.51) and <7 hours/night (1.29, 1.08-1.53). These associations were respectively attenuated after adjustment for demographic and clinical variables (adjusted OR 1.54, 95% CI 1.22-1.94 and 1.15, 0.96-1.38). Conclusion: Stroke survivors in the United States are more likely to have abnormal sleep duration compared to those without a prior stroke. Future research should explore the causal links between stroke by type and duration of sleep.