Abstract WP149: Racial Disparity In Intracerebral Hemorrhage Severity And Outcome: A 4-year Analysis Of The National Inpatient Sample From 2016-2019

Abstract

Background: Racial disparity in ICH management and outcome is a major concern. We sought to evaluate the impact of race on ICH severity and outcome in a nationally representative database. Methods: A query of the 2000-2019 National Inpatient Sample was performed for patients admitted with ICH (ICD9 431, 432.9, ICD-10 I61, I62.9). Demographics, comorbidities, and outcomes were identified. Discharge location was used as a surrogate for functional outcome. Univariate analysis with t-tests or chi-square performed as appropriate, and significant variables were entered into a multivariate regression to generate adjusted odds ratios (AOR)/β-coefficients for race on outcomes. Significance set at an alpha level of <0.001. All analysis performed in R version 4.1.3. Results: A total of 390,015 patients with ICH were identified over the four years; 97,220 (24.9%) had a reported NIH Stroke Score (NIHSS). Mean Age was 69.22 ± 14.3 years. Patients were 61% White, 16.6 % Black, 9.9% Hispanic, and 4.8% Asian. Average NIHSS differed significantly among the groups, with Asian patients having more severe disease than White, Black, or Hispanic patients (p<0.001). After multivariate analysis, Hispanic patients had greater odds of discharge home compared to White patients (AOR 1.3, 95% CI 1.12-1.51, p<0.05). Black patients had greater odds of discharge to nursing care facilities (AOR 1.12, 95%CI: 1.02-1.23, p<0.001). In hospital mortality was less in Black (AOR 0.7, 95%CI: 0.6-0.81), Asian (AOR 0.66, 95% CI: 0.51-0.83) and Hispanic (AOR 0.67, 95%CI: 0.55-0.8) patients (all <0.05). Conclusions: This nationally representative analysis demonstrates that Black patients have worse hospital outcomes after ICH while the rate of in-hospital mortality seen in Whites was higher in comparison to other races. White patients were the majority of cases and had an overall stable trend of good discharge outcome. Incidence of in-hospital mortality was highest in the Black patients over four years.