Abstract WMP12: Feasibility of Permanent Stenting With Solitaire Fr as a Rescue Treatment for the Reperfusion of Acute Intracranial Artery Occlusion

Abstract

Background and Purpose: Solitaire FR can be used not only as a tool for mechanical thrombectomy but also as a detachable permanent stent. Our aim was to assess the feasibility and safety of permanent stenting with Solitaire FR (erv3, Irvine, CA, USA) compared with other self-expanding stents for intracranial artery recanalization for acute ischemic stroke. Materials and Methods: From January 2011 through January 2016, 2,979 patients with acute ischemic stroke were retrospectively selected. Among them, 27 patients who underwent permanent stenting (13 patients with Solitaire FR (Solitaire group) and 14 patients with other self-expanding stents (other stent group)) were enrolled. The post-procedural mTICI grade and angiographic and clinical outcomes at discharge and 3 months were assessed. The safety and efficacy of permanent stenting of Solitaire FR stent placement for acute large arterial occlusion were evaluated. Results: Stent placement was successful in all cases. mTICI 2b-3 reperfusion was noted in 84.6% of Solitaire group and in 78.6% of other stent group. Procedure time was significantly shorter in Solitaire group than other stent group ( P = 0.022). No significant differences were found in mTICI grade, NIHSS score at discharge, mRS at 3 months, and rate of hemorrhagic transformation between the two groups. Acute in-stent thrombosis rate at discharge was significantly lower when glycoprotein IIb/IIIa inhibitor was injected during the procedure ( P = 0.013). Conclusions: Permanent stenting of Solitaire FR compared with other self-expanding stents appears to be feasible and safe as a rescue tool for refractory intra-arterial therapy.