Abstract W P328: Elevated Systolic Blood Pressure on Arrival is Not Associated with Higher Early Mortality in Intracerebral Hemorrhage Patients

Abstract

Background and Purpose: The role of blood pressure control in the initial management of patients with intracerebral hemorrhage (ICH) is an active area of clinical investigation. Although ICH score is a validated predictor of in-hospital mortality in patients with ICH, it is not known whether elevated systolic blood pressure (SBP) on arrival is predictive of early mortality. We hypothesized that elevated SBP on arrival would be associated with in-hospital mortality in primary ICH patients. Methods: We retrospectively analyzed consecutive spontaneous ICH patients at our institution from 2008-2013. Patients were excluded if they were under the care of a palliative physician. We examined demographics, vascular risk factors, stroke severity (NIHSS), ICH score, and laboratory values. Results: A total of 361 spontaneous ICH patients (median age 63, 43% black, 42% female) met inclusion criteria. Over half of ICH patients were transferred into our facility (54%). Sixty-four percent of patients arrived with SBP >160. The association of SBP on arrival and in-hospital mortality is depicted in Figure 1. Conclusions: After adjusting for ICH score, SBP was not a significant independent predictor of death during the hospitalization. This finding suggests that clinical trials of blood pressure management of patients with ICH should stratify patients according to ICH score.