Abstract W P300: Factors Affecting Functional Assessment Measures (FAM) Self-Completion Among Intracerebral Hemorrhage (ICH) Patients

Abstract

Background: The Barthel Index (BI) and Stroke Impact Scale (SIS) are established functional assessments measuring (FAM) performance in daily living activities and overall quality of health and life in stroke patients, respectively. Purpose: To determine factors affecting FAM self-completion among intracerebral hemorrhage (ICH) patients at 3 months post-stroke. Methods: Sample size consisted of 84 patients enrolled in an ICH clinical trial. Three categories were created to account for FAM completion: 1) Patient (P), 2) Family/Surrogate (F), 3) Missing/Not Required (M), which also included expired patients. To compare the differences between groups, analysis of variance, Kruskal-Wallis test or extended Fisher’s exact test, as appropriate, were performed. Results: BI was performed at baseline [n(%): P = 29 (34.5%), F = 55 (65.5%), M = 0 (0%)] and 3 months post-stroke [P = 45 (53.6%), F = 11 (13.1%), M = 28 (33.3%)]. SIS was performed at 3 months post-stroke [P = 43 (51.2%), F = 12 (14.3%), M = 29 (34.5%)]. Several baseline factors were scrutinized for their effect on FAM self-completion at 3 months. BI was significantly affected by: Stroke Scale (NIHSS), Glasgow Coma Scale (GCS), Modified Ranking Scale (mRS) and Hyperlipidemia. SIS was significantly affected by: NIHSS, GCS and aphasia. Larger baseline hematoma volumes (≥ 20.1cc), although not significant, also appeared to affect the study outcome. Conclusion: Patients presenting at baseline with NIHSS score ≥ 16, larger hematoma volumes, lower GCS, aphasia and hyperlipidemia were less likely to complete their own functional assessments by 3 months. Further study is necessary to explore additional FAM for severe ICH patients.