Abstract W P139: Normal Fasting Blood Sugar Level and K-Modified Barthel Index at 6 Months after Stroke: A Prospective Multicenter Study

Abstract

Introduction: Few studies investigated the relationship between the normal fasting blood sugar (FBS) level at onset and functional outcome (K-Modified Barthel Index; KMBI) at 6 months after stroke. Aims: The aim of this study is to investigate whether normal FBS level predicts 6-Month KBMI after adjustment for cardiovascular disease risk factors socioeconomic position and health behavior factors in Korean stroke patients. Methods: This is an interim report of the Korean Stroke Cohort for Functioning and Rehabilitation (KosCo). The sample included 816 ischemic stroke patients aged 18-92 years. KBMI score was assessed at 6 months after stroke onset. We divided subjects into three FBS levels according to FBS tertile: lower (70 ≤ FBS < 104 mg/dl), medium (104 ≤ FBS < 118 mg/dl), and higher (118 ≤ FBS < 140 mg/dl). Results: The mean age of subjects was 63.2 (±13.6) years. The mean of discharge KBMI and 6-month KBMI was 73.9 (±29.5) and 85.2 (±28.9), respectively. The mean of discharge KBMI for patients with lower, medium, and higher FBS level at onset was 77.7 (±26.8), 72.6 (±29.8), and 72.6 (±29.8), respectively (p<0.05); the mean of 6-Month KBMI 88.5 (±25.7), 84.9 (±29.5), and 82.2 (±31.1), respectively (p<0.05). The 6-Month KBMI significantly decreased in patients with higher FBS levels compared to lower FBS levels after adjustment for confounding factors (p<0.05). Conclusions: These hospital-based cohort study showed that higher FBS level at onset may predict poor functional outcome at 6 months after stroke (Supported by Korea Centers for Disease Control and Prevention (2013E3301701)).