Abstract
Background: The trends in utilization of Do-Not-Resuscitate Orders (DNR) and its effect upon outcomes among patients with intracerebral hemorrhage (ICH) is not studied within a national representative population. Objective: To identify the contemporary rate of utilization impact of DNR status on length of stay (LOS) and cost of care among patients (pts) admitted with ICH. Methods: We reviewed the Healthcare Cost and Utilization Project's Nationwide Inpatient Sample (NIS) database from 2011 for ICH using ICD 9-CM code (431) as a primary diagnosis. We defined patients’ DNR status with ICD CM code - V49.86 as a secondary diagnosis. Comorbid conditions were defined by Charlson's Comorbidity Index (CCI). Cost to charge ratio files were merged with NIS to calculate cost of care. LOS was calculated only in pts who were alive. T test was utilized for univariate analysis for continuous variable. Hierarchical multilevel regression models were generated to determine independent predictors of LOS and cost of care. Results: Total of 13440 pts (weighted: 64617) with ICH were analyzed, out of which 2029 pts (weighted: 9713) had DNR orders. Average LOS and cost of care for all ICH pts were 8.76 ± 0.12 days and $ 19386 ± 261, respectively. In univariate analysis, LOS and cost of care were lower in DNR pts (LOS: 5.76 ± 0.34 vs. 9.04± 0.13, p <0.001; Cost: $11020 ± 400 vs. $20916 ± 298, P <0.001). In multivariate analysis, the results were (days/cost, 95% CI, P-value) (LOS: -1.30 days, -2.26 - -0.35, p<0.001; cost: $ -5509, -6851 - -4168, p<0.001). Elective admission was associated with decrease in cost (Cost: $ -2439, -4506 - -372, p=0.02). Pts with private insurance were more likely to have decrease LOS and cost of care (LOS: -1.62, -2.35 - -0.90, p<0.001; Cost: -1439, -2745 - -132, p=0.03) as compared with Medicare/Medicaid. Hospital teaching status was associated increase in cost of care while self pay/others was associated with decrease in cost of care. CCI >= 3 was associated with increase in both cost of care and LOS as compared to CCI= 1. Conclusions: DNR status in patient with ICH is a predictor of a significantly lower LOS and cost of care. Appropriate use of DNR status may reduce LOS and cost of care in ICH patients and decrease inappropriate resource utilization.
Published Version
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