Abstract TP7: Isolated Basal Ganglia Strokes Undergoing Thrombectomy Have High Rates of Good Clinical Outcomes

Abstract

Background and Purpose: Isolated basal ganglia strokes are thought to have worse clinical outcomes as compared to mixed and cortical infarcts. Methods: Review of a prospectively collected database of endovascular patients with anterior circulation Large vessel occlusion strokes from January 2014-June 2018. Only patients with an ASPECT score of 6 to 9 were included. Patients were dichotomized into 2 groups according to ASPECT region involvement: (i) isolated basal ganglia and (iBG) (ii) other stroke patterns. Baseline characteristics and Clinical outcomes were compared. Results: 465 patients qualified for the study of which 324 (70%) were iBG strokes. Baseline characteristics were comparable between the 2 groups except for higher rates of hypertension (73.8%vs63.8%,p=0.03) and larger CTP core infarct (3.6 cc[0-13] vs 3[0-10.85], p<0.001) in the iBG group. There were no differences between groups in rates of successful reperfusion (mTICI 2b-3) (97.2% for iBG vs96.5%, p=0.66), any parenchymal hematomas (9.4%vs11.4%, p=0.49) and rates of good outcomes (mRS 0-2) (53.7% vs 50.4%, p=0.55). iBG patients had lower 90-day mortality rates (13.1%vs23.3, p=0.01). This persisted as non-statistically significant trend after adjusting for potential confounders (OR 0.54 95%CI [0.277-1.03],p=0.06) Conclusions: iBG strokes carry similar procedural and clinical outcomes as other stroke patterns with a trend towards lower mortality.