Abstract TP281: Ischemic Stroke Risk in Transient Global Amnesia

Abstract

Introduction: There has been much debate on whether transient global amnesia (TGA) increases the risk for subsequent cerebrovascular events. This study aims to assess whether certain comorbidities may increase risk for a future ischemic event. Methods: We retrospectively identified patients within the Southern California KP region using ICD 9 and ICD-10 codes who had a diagnosis of TGA from 2012-2017. Patients with prior history of stroke or TIA were excluded. We then evaluated differences in baseline demographics and characteristics in patients who were admitted to the hospital with an ischemic stroke within five years compared to those who were not. Results: There were 136 patients diagnosed with TGA between 2012-2017. Of 136, 10 (7.4%) were admitted with an acute stroke. There were no differences in age, gender, or race/ethnicity between those who had a stroke versus those that did not. In terms of vascular risk factors, those who had history of coronary artery disease (CAD) or prior MI were more likely to have a stroke compared to those who did not {6 (60%) vs. 26 (20.8%), p = 0.005}. There were no differences in other risk factors. Conclusion: After the diagnosis of TGA, those who have a history of CAD or prior MI were more likely to have an ischemic stroke within five years.div>