Abstract

Racial and ethnic disparities in risk factors and outcomes for young patients with ischemic stroke (AIS) are well described. Less is known about disparities in risk and outcomes for young patients presenting with intracerebral hemorrhage (ICH), which is associated with higher short-term and long-term mortality. As such, it is important to review disparities in its evaluation and management. In this study, we aimed to evaluate racial and ethnic differences in risk factors and outcomes for young patients with ICH. Methods: We identified patients aged 18-45 from our inpatient stroke registry who presented to our comprehensive stroke center with non-traumatic ICH from 10/2016 to 11/2019, with exclusion of patients with primary subarachnoid hemorrhage. We abstracted baseline characteristics and compared ICH risk and outcomes amongst different racial groups and ethnicities through examination of sociodemographic and medical risk factors and outcomes using independent samples t-test for continuous outcomes, and chi-squared test for categorical outcomes. All tests were two-tailed and the error rate was set at 5%. Results: Among 430 patients who met inclusion criteria, 22.3% were non-Hispanic White (NHW), 31.6% Non-Hispanic Black(NHB), 28.6% Hispanic (HIS), 4.9% Asian, and 5.1% other. There were significant differences in insured status, with 50.4% of HIS having insurance compared to 67.6% of NHB and 68.8% of NHW patients. NHB and HIS patients were more likely to be single (55.1% and 44.7%), compared to NHW (32.3%) and Asian (38.1%) patients. Black patients had the highest likelihood of living alone (20.6%; p=0.07), while Hispanic patients were more likely not to not have a primary care provider (64.2%; p=0.02). NHB patients were more likely to have prior hypertension (72%), and diastolic dysfunction (27.2%) compared to NHW (53.1%, 13.5%), and HIS (50.4%, 11.4%) patients). No significant differences in overall discharge disposition or mRS was noted when comparing racial and ethnic groups. Conclusion: Although we did not find significant differences in measured outcomes, our study demonstrates underlying sociodemographic and clinical risk factors which may underlie racial and ethnic disparities in long-term outcomes for patients with ICH.

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