Abstract
Introduction: As far as we are aware, there are no published studies that have examined the influence of sex on U.S. national short-term readmission rates after hospitalization for an index ischemic stroke. Baseline differences between men and women (eg, age, comorbidities, risk factor profiles, stroke severity, and pre-stroke disability) can have an impact on early readmissions, the latter of which, are associated with worse clinical outcomes and excess medical costs. Methods: Patients with ischemic stroke were extracted from the 2014 National Readmission Database. Multivariable logistic regression analysis was used to identify independent predictors of 30-day readmission after ischemic stroke. Results: A sample of 230,869 ischemic stroke patients (weighted N= 502,604) were included in this study, 48.86% were women. Female had statistically and significantly lower odds of 30-days readmission (OR=0.865; 95% CI: 0.816-0.917) than male. Conclusion: In this national representative sample analysis, we found that females were 14% less likely compared to males to be readmitted. Other predictors of 30 day readmission included age, length of stay, and comorbidity severity. Understanding the interaction of sex on these factors may help to reduce health care costs and improve quality of life in stroke survivors.
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