Abstract TP139: Utilization and Outcomes of Extracranial-Intracranial Bypass Surgery in Adult Moyamoya Population

Abstract

Introduction: The Extracranial-Intracranial bypass (EC-IC) surgery is performed to restore blood flow to the brain and prevent both hemorrhagic and ischemic strokes in Moyamoya disease (MMD) patients. There is a lack of contemporary data regarding EC-IC utilization, racial disparities, related mortality, and disability in the US. Method: Using ICD 9-CM codes 437.5 and 39.28, MMD and EC-IC procedures were extracted from National Inpatient Sample 2005-2015. The weighted discharge was used to generate national estimates. Predictors of revascularization utilization were evaluated using multivariable logistic regression analysis to avoid confounding effect. Disability was defined as non-home discharges, after excluding mortality. Results: Of total 24,484 admissions for MMD, 3,965 (16.2%) underwent revascularization. The mean age of revascularization patients was (SE) ~42 (0.52) years and F: M ratio of 3:1. After multivariable logistic model analysis, higher utilization rates were found in 40-59 year age group (48.3%, OR:1.29; P=0.02), who had ischemic strokes (9.2%, OR:1.38; P=0.03), and conventional cerebral angiography (30.2%, OR:1.80; P=0.001). Lower utilization rates were found in African Americans (14.9%, OR: 0.66; P=0.004), Hispanics (5.7%, OR: 0.60; P=0.03), Medicare recipients (13.6%, OR: 0.55; P=0.009), Northeast (11.5%, OR: 0.47; P= 0.003), Midwest (22.7%, OR: 0.55; P= 0.02), and South (24.8%, OR: 0.46; P=0.0002) compared to the West region. There is no utilization difference in gender female (72.4%, OR: 0.89; P=0.36). After EC-IC surgery, 79% were discharged home, 21% discharged to assistive facilities, and 0.6% died. After adjusting for hospital characteristics and associated comorbidities, lower disability (OR: 0.75; P=0.04) and the mortality rate was reported (OR: 0.80; P=0.71) among revascularization. Conclusions: This nationally representative date within the US suggests that though there is no gender disparity in utilization of EC-IC bypass surgery, there is a significant racial and regional disparity in the utilization of the procedure. Patients undergoing revascularization had better functional outcomes. Further research is needed to identify potential predictors for underutilization in these cohorts.