Abstract TP132: Racial Disparity In Outcomes Of Primary Intracerebral Hemorrhage In The United States: A 20-year Analysis Of The National Inpatient Sample

Abstract

Background: Primary intracerebral hemorrhage (ICH) is a devastating disease with limited therapeutic options and poor overall outcomes. We aimed to characterize racial disparities in patients with ICH over a 20 year period and examine the prognostic impact of race on functional outcomes. Methods: A query of the 2000-2019 National Inpatient Sample was performed for patients admitted with ICH (ICD9 431, 432.9, ICD-10 I61, I62.9). Demographics, comorbidities, and outcomes were identified. Discharge location was used as a surrogate for functional outcome. Univariate analysis with t-tests or chi-square performed as appropriate, and significant variables were entered into a multivariate regression to generate adjusted odds ratios (AOR)/β-coefficients for race on outcomes. Significance set at an alpha level of <0.001. All analysis performed in R version 4.1.3. Results: A total of 2,000,868 patients with ICH were identified. Mean Age was 68.28 ±15.41 years. Patients were 57.2% White, 14.1 % Black, 8.3% Hispanic, and 3.9% Asian. Average Elixhauser Comorbidity Score was significantly different among the groups, with White patients having higher score on average than Asian, Black, or Hispanic Patients. There was no difference in NIH Stroke Scale among the groups. After multivariate analysis, there were no differences in odds of discharge to home or to nursing/long-term care facilities between races (p>0.001). In hospital mortality was less in Black (AOR 0.73, 95%CI: 0.64-0.84) and Hispanic (AOR 0.65, 95% CI: 0.55-0.78) patients compared to White (p<0.001). Conclusions: This 20 year nationally representative analysis of racial disparities in ICH patients shows that despite the increasing prevalence in Black and Hispanic patients over 20 years, they have greater odds of survival during their hospital stay when compared to White patients. Further examination of healthcare systems and patient-specific factors are warranted to elucidate this phenomenon.