Abstract TP122: Comparison Of Pharmacologic And Physical Venous Thromboembolism Prophylaxis: A Single Center Descriptive Analysis

Abstract

Introduction: Recent American Heart Association/American Stroke Association guidelines suggest that physical venous thromboembolism (VTE) prophylaxis modalities are effective at preventing VTE events. Objective: To compare the incidence of VTE events among AIS patients receiving either pharmacologic prophylaxis or physical prophylaxis during hospitalization. Methods: Single center data was retrospectively analyzed among AIS patients who developed DVT or PE during their hospitalization. Patients were selected from January 1, 2016 - December 31, 2020. Inclusion criteria included age 18 and above, AIS patients, diagnosis of acute or chronic VTE events, and exclusive use of physical or pharmacologic VTE prophylaxis modality. We excluded patients who received combined SCD and pharmacologic prophylaxis during hospitalization. Results: Of 5104 patients diagnosed with AIS, 40 patients (0.8%) developed VTE events during their hospitalization. Of these, 29/40 (73%) received pharmacologic VTE prophylaxis and 11/40 (27%) received physical VTE prophylaxis. Of the 3488 patients receiving pharmacologic VTE prophylaxis, 29 (0.8%) developed VTE. Of the 1616 that received physical VTE prophylaxis, 11 (0.7%) developed VTE. Conclusions: Our single center study observed higher rates of VTE events among AIS patients receiving pharmacologic VTE prophylaxis in comparison to physical VTE prophylaxis.