Abstract T P11: Motor Component of National Institute of Health Stroke Scale Effect on Functional Outcome and Mortality at Discharge in Patient Receiving Endovascular Therapy

Abstract

Background and Purpose: Predicting the patient outcome after a vascular event can be very challenging. The National Institute of Health (NIH) developed a standardized scale to evaluate the severity of a stroke at presentation. The objective of this analysis was to study the effect of the motor component of the NIH Stroke Scale (NIHSS) on a patient’s functional outcome at discharge. Methods: This is a retrospective analysis of all patients (n= 97) that presented to our hospital with ischemic stroke and received mechanical thrombectomy between January 2009 and July 2012 and had all the components of NIHSS baseline documented at presentation. Statistical analysis was performed using the R statistical package and XLSTAT-Pro 2011. Spearman correlations (P value <0.05) for non-normally distributed data were used to independently evaluate the correlation of each of the NIHSS components with patient functional outcome at discharge using modified rankin scale (mRS). mRS of 2 or less represented a good functional outcome. Results: Group analysis including gender, mean age, mean NIHSS and mortality at discharge was as follows: Female 49.5%, 72.9, 14.7 and 13.4%. All Motor components of NIHSS had a significant correlation (Rho=0.24, P value <0.05) with poor patient outcome at discharge, meaning a higher motor score at presentation represented a worse outcome at discharge. A higher NIHSS had a significant correlation with poor functional outcome (Rho=0.41, P value <0.05). Conclusion: In conclusion, admission motor grade may serve as a good predictor of disability and mortality in patients undergoing mechanical thrombectomy with acute ischemic stroke. Further validation by a prospective study with a larger sample size is warranted.