Abstract PS7-71: Breast cancer fast-track programme to shorten time between initial symptoms, diagnosis and initiation of treatment. 10 years update

Abstract

Abstract Background: Breast cancer (BC) is one of the most serious health problems worldwide. The implementation of screening programs as well as advances in diagnosis and therapeutics have achieved an increase in survival. However, there are patients who do not benefit from screening programs: very young or older than 69 years old patients and interval cancers.The main aim of this breast cancer fast-track program (BCFP) is to reduce the time from the onset of breast cancer signs and symptoms until the beginning of treatment. · Methods: The programme began in June 2009; we hereby present data from the first ten years (June 2009-June 2019) in the Clinico-Malvarrosa Health Department in Valencia, Spain. Breast surgeons, primary care (PC) physicians, radiologists who are experts in breast cancer and oncology coordinators regularly met to discuss suspected cases of BC, and initially set guidelines with the criteria to be used by PC physicians in order to refer patients to BCFP. On the same day that the PC physician identified a patient with suspected BC, an index card was sent to the oncology coordinator, who reviewed these cases and referred those meeting previously defined criteria to either breast surgeons or breast radiologists. · Results: 1849 proposals were sent to the hospital from which 1778 patients came to the first visit at the specialist. 312 (16.9%) referred cases were diagnosed with BC. 206 (66%) women were diagnosed of BC in the age range in which screening with mammography is not recommended in our general population (between 45-69 years old). 296 patients had a localized BC (94%) and 16 (6%) an advanced BC. The median time from submission of a proposal until the specialist assessment was 13 days for diagnosed patients, 2 days from the first visit to histopathological diagnosis, and 29 days from the histopathological diagnosis until a treatment is initiated (either oncological or surgical). It took a median of 18 days to confirm the absence of BC in 1466 patients with initial suspicion of it. • Conclusions: Our data show that the time interval between patient referral by the PC physician to the specialist, diagnosis of breast cancer, and start of therapy can be reduced. We optimized existing resources with no additional costs associated with the implementation of this programme. Keywords: Breast Cancer, Clinical Guidelines, Early diagnosis Authors: M.T. Martinez1*, S. Moragon1*, S. Simón1, B. Ortega1, J.V. Montón1, J. Navarro2, A. Sanmartin2, A. Julve3, E. Buch4, O. Burgues5, C. Hernando1, J. M. Cejalvo1, A. Lluch1, B. Bermejo1, A. Cervantes1, I. Chirivella1.1Medical Oncology Department, INCLIVA Biomedical Research Institute, Valencia, Spain, 2Management department, Hospital Clinico Universitario de Valencia, Valencia, Spain3 Radiodiagnosis Department, Hospital Clinico Universitario de Valencia, Valencia, Spain4 Senology Department, Hospital Clinico Universitario de Valencia, Valencia, Spain5 Pathological Anatomy Department. Hospital Clinico Universitario de Valencia, Valencia, Spain Citation Format: Maria Teresa Martínez, Santiago Moragon, Soraya Simon, Belen Ortega, Jose Vicente Monton-Bueno, Jorge Navarro, Ana Sanmartin, Ana Julve, Elvira Buch, Octavio Burgués, Cristina Hernando, Juan Miguel Cejalvo, Ana Lluch, Begoña Bermejo, Andrés Cervantes, Isabel Chirivella. Breast cancer fast-track programme to shorten time between initial symptoms, diagnosis and initiation of treatment. 10 years update [abstract]. In: Proceedings of the 2020 San Antonio Breast Cancer Virtual Symposium; 2020 Dec 8-11; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2021;81(4 Suppl):Abstract nr PS7-71.